Effects of different level of arginine on antioxidant status, serum carotenoid levels and carcass traits in broilers challenged with Eimeria spp

نوع مقاله : مقاله پژوهشی


1 , Department of Animal Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran

2 Department of Pathobiology, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran

3 Department of Animal Science, Faculty of Agriculture, University of Tabriz, Tabriz, Iran

4 Department of Animal Science, Faculty of Agriculture, University of Birjand, Birjand, Iran


زمینه مطالعاتی: کوکسیدیوز یکی از رایج‏ترین بیماری‏ها در صنعت طیور در سرتاسر جهان است که با انتریت شناخته می‏شود. کوکسیدیوز باعث ایجاد زیان‏های اقتصادی در طیور جوان می‏شود، زیرا سبب مرگ‏ومیر و اسهال می‏شود. این بیماری غلظت پلاسمایی آرژنین را کاهش می‏دهد و سیستم آنتی اکسیدانی را سرکوب می‏کند. هدف: این مطالعه با هدف ارزیابی اثرات آرژینین بر وضعیت آنتی اکسیدانی، صفات لاشه و سطوح سرمی کاروتونوئیدها در جوجه‏های چالش یافته با گونه‏های آیمریا انجام شد. روش کار: تعداد 384 جوجه‏ی گوشتی نژاد راس از هردو جنس به 8 گروه، با 6 تکرار و 8 پرنده در هر تکرار تقسیم بندی شدند و تا 21 روزگی در شرایط مشابهی پرورش یافتند. در روز 21، جوجه‏های گوشتی با گونه‏های آیمریا چالش یافتند. جوجه‏های گوشتی به دو بخش عفونی و غیر عفونی تقسیم بندی شدند و سطوح (85، 100، 125 و 150%) آرژنین را دریافت کردند. سطوح آنزیم‏های آنتی اکسیدان، مالون دی‏آلدهید، نیتریک اکسید، صفات لاشه و سطوح کاروتنوئیدها ارزیابی شدند. نتایج: نتایج نشان داد که چالش با کوکسیدیوز ظرفیت تام آنتی اکسیدانی و سطح کاروتنوئیدها را کاهش داد ولی سطح مالون دی‏آلدهید و سطح نیتریک اکسید را در مقایسه با گروه‏های غیر عفونی افزایش داد (0.05p <). افزودن آرژینین به جیره در سطوح 125% و 150% ظرفیت تام آنتی اکسیدانی و سطح کاروتنوئیدها را افزایش داد ولی سطح مالون دی‏آلدهید و سطح نیتریک اکسید را در مقایسه با گروه‏های غیر عفونی کاهش داد (0.05p <). نتیجه‏گیری: در مجموع، کوکسیدیوز ظرفیت تام آنتی اکسیدانی و سطح کاروتنوئیدها را کاهش داد و سطح مالون دی‏آلدهید و سطح نیتریک اکسید را در مقایسه با گروه‏های غیر عفونی افزایش داد، ولی سطوح بزرگتر آرژینین اثرات منفی عفونت را کاهش داد. در مجموع، می‏توان بیان نمود که سطوح بزرگتر آرژینین وضعیت آنتی اکسیدانی را در شرایط عفونی بهبود بخشید.


عنوان مقاله [English]

Effects of different level of arginine on antioxidant status, serum carotenoid levels and carcass traits in broilers challenged with Eimeria spp

نویسندگان [English]

  • F Izadi yazdanabadi 1
  • Gh Moghaddam 1
  • A Nematollahi 2
  • H Daghighkia 3
  • H Sarir 4
چکیده [English]

Introduction: Coccidiosis is one of the most common diseases in poultry industry in all over the world that is characterized by enteritis. Coccidiosis causes economic losses in chicks, because it induces diarrhea and deaths. This disease decreases the plasma concentration of arginine and suppresses antioxidant system. This study aimed to evaluate the effects of different levels of arginine on antioxidant status, carcass traits, and serum carotenoid levels in broiler chicks challenged with Eimeria spp. Materials and Methods: A total number of 384 one-day-old broiler chicks (Ross 308) of mixed sex was allocated into 8 groups with 8 birds/pen from grower period. At 21 days, broiler chickens were challenged with a mixture of Eimeria species. Birds were divided into infected and uninfected groups and received arginine at 85, 100, 125, and 150 % of recommended levels. The levels of antioxidant enzymes, malondialdehyde (MDA), nitric oxide (NO), and serum carotenoid levels were assessed in blood sera and also carcass traits were evaluated. Results: Coccidiosis decreased total antioxidant capacity, and serum carotenoid levels, but increased MDA and NO in comparison with uninfected Birds (p < /em><0.05). However, 125 and 150% diets, increased total antioxidant capacity and serum carotenoid levels, but decreased MDA (p < /em><0.05). Conclusion: In conclusion, coccidiosis decreased antioxidant status and serum carotenoid levels in broiler, but dietary inclusion of higher levels of arginine improved antioxidant status and serum carotenoid levels. In summary, higher levels of arginine could be recommended to improve antioxidant capacity and serum carotenoid levels in broiler challenged with coccidiosis.

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